Description:

Represents the first focused book on the field of Adaptive Radiation Therapy

Presents contributions from world-class leaders in their respective fields

Covers 3D and 4D morphological and biological imaging approaches to radiation treatment planning

Discusses treatment delivery across various modalities

Provides examples from state-of-the-art in radiation therapy for brain tumors, head and neck cancer, and breast cancer

Adaptive Radiation Therapy (ART) has the ability to achieve highly individualized radiation treatment of cancer patients through customized planning and delivery. This comprehensive book covers treatment planning aspects, including uses of patient-specific spatial morphological and biological information for target definition; methods to optimize plans based on the patient-specific information; and techniques to assess treatment response for feedback. It discusses technologies for treatment delivery across various modalities and presents clinical examples that demonstrate modern applications of ART. World-class experts discuss state-of-the-art radiation therapy for brain tumors, head and neck cancer, sarcomas, and breast cancer.

Table of Contents:

Treatment planning and delivery of physically and biologically adaptive radiation therapy: An introduction. Part I. Treatment Planning. Goals of radiation therapy. 3D and 4D Morphological imaging for radiation treatment planning. Biological Imaging for Radiation Treatment Planning. Biomarkers for early radiation response. Inverse treatment planning. Biologically-based models for treatment planning. Tumor Radiation Response assessment and feedback for treatment planning. Normal Tissue Radiation Response Assessment and Feedback for treatment planning. Part II. Treatment Delivery. IMRT delivery. CT-based IGRT technology. Non-CT based IGRT. Off-line Correction Strategies for interfraction variations. Online Correction strategies for interfraction variations. Intrafraction Variations and Management Technologies. Stereotactic radiation therapy delivery. Image-guide brachytherapy. Quality Assurance in Adaptive Radiation Therapy. Part III. Clinical Applications. Adaptive Radiation Therapy for Central Nervous System. Adaptive Radiation Therapy for Head and Neck. Adaptive Radiation therapy for Breast. Adaptive Radiation Therapy for Lung. Adaptive Radiation Therapy for Liver. Adaptive Radiation Therapy for Prostate. Adaptive Radiation Therapy for Sarcoma.