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| Cell Migration: Signalling and Mechanisms | |
| A unique synopsis for cell biologists, immunologists and oncologists | |
| Edited by: Entschladen F. Entschladen F. | |
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Description:
 Cell migration is a highly complex process which involves several
compartments of the cell, including surface receptors, signalling
elements and the cytoskeleton. It plays an essential role in
embryogenesis, wound healing and inflammatory responses, and a
dysregulation of cell movement can cause pathological states such as
developmental defects, chronic inflammation, cancer invasion and
metastasis.
Covering extracellular regulatory signals and intracellular signal
transduction pathways as well as the molecular mechanisms of migration
in stem cells, leukocytes and tumor cells in the adult human organism,
this book summarizes the current state of knowledge about cell
migration. In the first part, the major aspects of different migratory
cells in health and disease are covered, with special emphasis on T
lymphocytes. The second part provides a comprehensive overview of the
principal molecular mechanisms of migration such as adhesion receptors,
cytoskeletal rearrangements and locomotor force generation, which,
together, can be referred to as a cell’s ‘migrosome’.
With contributions by eminent international scientists from
different disciplines this book will serve as a valuable resource not
only for researchers in cell biology, immunology and oncology, but also
for clinicians who wish to learn more about the role of migratory
processes in health and disease.
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| Edited by: Entschladen F. Entschladen F. |
| 176 Pages, Illustrations: 20 fig., 2 tab., hard cover, 2010 |
| $179.00 U.S.
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| ISBN: 978-3-8055-9321-2
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| email: info@advmedpub.net |
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