This Fourth Edition reflects the significant recent progress that has occurred in the field of functional brain imaging, particularly the increased use of PET/SPECT, the use of SPECT and PET in movement disorders and dementia, and advances in radiopharmaceutical development and instrumentation. Chapter topics include PET physics and instrumentation, PET radiopharmaceuticals, SPECT radiopharmaceuticals, and technical factors.

The entire book has been thoroughly revised to reflect an appropriate balance between SPECT and PET applications. Highlights of this edition include a new chapter on neuroreceptor imaging and kinetic modeling, a new chapter on brain imaging in movement disorders, and significant updates on SPECT radiopharmaceuticals.

Table of Contents:

Section I: GENERAL ASPECTS OF SPECT/PET BRAIN IMAGING

1: SPECT Functional Brain Imaging: Instrumentation, Radiopharmaceuticals and Technical Factors
Michael D. Devous, Sr.

2: PET Physics and Instrumentation
Peter D. Esser

3: PET Radiopharmaceuticals
William C. Eckelman and John W. Babich

4: Neuroreceptor Imaging and Kinetic Modeling
Masanori Ichise

5: Normal Structural and Functional Neuroanatomy for SPECT and PET Imaging
Joseph C. Masdeu, Bela Ajtai, David K. Leung, Angleia Ligneli, and Masanori Ichise

6: Functional Anatomy and SPECT Imaging
H. Branch Coslett

Section II: CLINICAL DISEASE STATES

7: Dementia: Diagnosis of Dementia
Ronald L. Van Heertum

8: Cerebrovascular Disease: SPECT/PET
James M. Mountz

9: Epilepsy: Positron Emission Tomography
William H. Theodore

10: Epilepsy Localization: Ictal and Interictal SPECT
Sun Hee Kim, I. George Zubal, and Hal Blumenfeld

11: Movement Disorders
John P. Seibyl

12: Traumatic Brain Injury: SPECT and PET
Ronald S. Tikofsky

13: Primary Brain Tumors: PET
Lutz W. Kracht

14: Psychiatric Disorders
Jong-Hoon Kim and Anissa Abi-Dargham

15: Addictive Disorders
Bryon Adinoff, Anthony Mazzarulli, and Michael D. Devous, Sr.

Section II: CASES

A: Examples of Normal SPECT and PET Images: Helpful Hints for Interpretation

B: Dementia

C: Cerebrovascular Disease

D: Epilepsy

E: Movement Disorders

F: Traumatic Brain Injury

G: Brain Tumors

H: Psychiatric Disorders

I: Addictive Disorders

J: Miscellaneous