Description:

Michael J. Droller, MD and a panel of experienced clinicians bring their strong background in clinical research to bear on the assessment and management of bladder cancer. Their comprehensive discussion summarizes the state-of-the-art in diagnosis and treatment, based on the latest understanding of bladder cancer’s epidemiology, carcinogenesis, and tumor markers. Topics of particular interest include the role of genetics and molecular biology in evaluating bladder cancer clinically, the evaluation of the results of systemic treatment in advanced disease, the current status of tumor markers in bladder cancer, and the means for further study in their applicability. Insightful and evidenced-based, Bladder Cancer: Current Diagnosis and Treatment provides active clinicians and clinical investigators with not only a critical survey of the rapidly expanding research in the area, but also a state-of-the-art tutorial on today’s optimal assessment and treatment of bladder cancer.

Contents:

Demographic and Epidemiologic Aspects of Bladder Cancer, Gunnar Steineck. Biology and Molecular Aspects of Development and Progress of Bladder Cancer, Dan Theodorescu and William A. See. Diagnosis of Bladder Cancer, Ichabod Jung, Edward M. Messing and Yves Fradet. Diagnostic Imaging in Urothelial Cancer,Lynn Ladetsky, Harold Mitty and Rosaleen B. Parsons. Urinary Cytology and Its Role in Diagnosis and Monitoring in Urothelial Carcinoma, Hans Wijkström, William C. Baker, Arline D. Deitch and Ralph W. deVere White. The Use of Tumor Markers in Bladder Cancer and Current Concepts on Clinical Applicability, H. Barton Grossman. Pathologic Assessment of Bladder Cancer and Pitfalls In Staging, Christer Busch, Debra Hawes, Sonny L. Johansson and Richard J. Cote. Use of Intravesical Chemotherapy in Treatment of Superficial Bladder Cancer, Vincent G. Bird, Mark S. Soloway and Per-Uno Malmström. Use of Intravesical BCG in Treatment of Superficial Bladder Cancer, Michael A. O’Donnell. Radical Cystectomy and Pelvic Lymphadenectomy in the Treatment of Infiltrative Bladder Cancer, John P. Stein, Donald G. Skinner and James E. Montie. Considerations in the Use of Neoadjuvant and Adjunctive Systemic Chemotherapy in Treatment of Invasive Bladder Cancer by Cystectomy, Seth P. Lerner and Derek Raghavan. Clinical Situations for the Role of Radiation in the Treatment of Bladder Cancer, Mary K. Gospodarowicz, M.F. Milosevic, P. Warde and Arthur Porter. Current Concepts for Urinary Diversion in Men, Courtney M.P. Hollowell, Gary D. Steinberg and Randall G. Rowland. Current Concepts of Urinary Diversion in Women, Arnulf Stenzl and Georg Bartsch. Current Prospects for the Use of Molecular Markers in Treatment of Bladder Cancer by Cystectomy or Bladder-Conserving Approaches, Guido Dalbagni, Carlos Cordon-Cardo and Joel Sheinfeld. New Possibilities in Systemic Treatment for Metastatic Bladder Cancer, Randall F. Millikan and Simon Hall. Statistical Consideration in the Phase 2 Evaluation of New Therapy. Randall F. Millikan and Peter F. Thal.