This comprehensive and
critical review of current and established treatment modalities for
malignant liver tumors is designed to help you sort through the
proliferation of competitive approaches and choose the best treatment
options for your patient. Dr. Clavien and his contributors consider all
the options – radiological, surgical, pharmaceutical, and emerging/novel
therapies – and help you find the best single or combined therapy.
Building on the success of the previous edition, this extremely thorough
revision:
- features a new section on Guidelines for Liver Tumors, where you
will find specific strategies for treating common liver malignancies;
the guidelines were prepared by the Associate Editors and take into
account national and international society guidelines
- reflects actual practice by taking a multidisciplinary
approach, with contributions from international experts who have
extensive experience with this patient population
- achieves comprehensive and balanced coverage by having each
chapter reviewed by the Editor, Deputy Editor, two Associate Editors,
and at least one external reviewer
- includes 16 new chapters that cover liver anatomy, histologic
changes in the liver, epidemiology and natural history of HCC, CCC and
colorectal liver metastases, strategies of liver resection, and economic
aspects as well as novel therapies
- facilitates the kind of daily interaction among hepatologists,
hepatic surgeons, medical oncologists, radiotherapists, and
interventional radiologists that is essential when treating patients
with complex liver malignancies
In 44 chapters organized into six major sections, the book covers the
full range of liver tumors. The perfect blend of evidence and
experience, Malignant Liver Tumors: Current and Emerging Therapies, 3rd
Edition, illuminates the path to better patient care.
Table of Contents:
Contributors.
Preface.
Acknowledgments.
Abbreviations.
Section 1 Introduction.
1 From Promethean to Modern Times (Kuno Lehmann, Stefan Breitenstein,
and Pierre-Alain Clavien).
2 Hepatic Anatomy and Terminology (Steven M. Strasberg).
Section 2 Epidemiology and Diagnosis.
Introduction (Chung-Mau Lo).
3 Histology and Pathology of Normal and Diseased Liver (Valérie
Paradis and Achim Weber).
4 Pathology of Primary and Secondary Malignant Liver Tumors (Kay
Washington).
5 Epidemiology, Etiology, and Natural History of Hepatocellular
Carcinoma (Wei-Chen Lee and Miin-Fu Chen).
6 Epidemiology, Etiology, and Natural History of Cholangiocarcinoma (Peter
Neuhaus, Ulf P. Neumann, and Daniel Seehofer).
7 Epidemiology, Etiology, and Natural History of Colorectal Liver
Metastases (Robert J. Porte).
8 Tumor Markers in Primary and Secondary Liver Tumors (Ketsia B.
Pierre and Ravi S. Chari).
9 Modalities for Imaging Liver Tumors (Dominik Weishaupt and Thomas
F. Hany).
Section 3 Systemic and Regional Therapies.
Introduction (Ravi S. Chari).
10 Systemic Treatment of Hepatobiliary Tumors (Panagiotis Samaras,
Michael A. Morse, and Bernhard C. Pestalozzi).
11 External Beam Radiation Therapy for Liver Tumors (Rakesh Reddy and
A. Bapsi Chakravarthy).
12 Internal Radiation Therapy for Liver Tumors (Ahsun Riaz, Laura
Kulik, Michael Abecassis, and Riad Salem).
13 Transarterial Embolization for Patients with Hepatocellular Carcinoma
(Jordi Bruix, Carmen Ayuso, and Maria I. Real).
14 Selective Continuous Intra-arterial Chemotherapy for Liver Tumors (Fidel
D. Huitzil-Melendez, Stefan Breitenstein, and Nancy Kemeny).
15 Isolated Hepatic Perfusion and Percutaneous Hepatic Perfusion (Charles
K. Heller, III, James F. Pingpank, and Steven K. Libutti).
Section 4 Resection, Ablation or Transplantation for Liver Tumors.
Introduction (Jean-Nicolas Vauthey and Tadatoshi Takayama).
16 Liver Resection of Primary Tumors: Hepatocellular Carcinoma,
Cholangiocarcinoma, and Gallbladder Cancer (Tadatoshi Takayama and
Masatoshi Makuuchi).
17 Liver Resection of Colorectal Liver Metastases (Daria Zorzi, Yun
Shin Chun, and Jean-Nicolas Vauthey).
18 Laparoscopic Liver Resection (Luca Viganò and Daniel Cherqui).
19 Repeat Resection for Liver Tumors (Mickael Lesurtel and Henrik
Petrowsky).
20 Cryoablation of Liver Tumors (Sivakumar Gananadha and David L.
Morris).
21 Thermal Ablation of Liver Tumors by Radiofrequency, Microwave, and
Laser Therapy (M. B. Majella Doyle and David C. Linehan).
22 Ethanol and Other Percutaneous Injection Modalities in the Treatment
of Liver Tumors (Michael A. Heneghan and Andrew D. Yeoman).
23 Transplantation for Liver Tumors (François Durand, Claire Francoz,
and Jacques Belghiti).
24 Preventing Recurrence of Hepatocellular Carcinoma after Curative
Resection (Stefan Breitenstein, Dimitris Dimitroulis, and Beat
Müllhaupt).
Section 5 Guidelines for Liver Tumor Treatment.
Introduction (Stefan Breitenstein and Pierre-Alain Clavien).
25 Strategies for Safer Liver Surgery (Philipp Dutkowski, Olivier de
Rougemont, and Pierre-Alain Clavien).
26 Hepatocellular Carcinoma (Tadatoshi Takayama).
27 Cholangiocarcinoma (Jacques Belghiti and Charles B. Rosen).
28 Gallbladder Cancer (Juan Hepp and Chung-Mau Lo).
29 Colorectal Liver Metastases (Phuong L. Doan, Jean-Nicolas Vauthey,
Martin Palavecino, and Michael A. Morse).
Section 6 Emerging Therapies.
Introduction (Michael A. Morse and Josep M. Llovet).
30 Viral-Based Therapies for Primary and Secondary Liver Cancer (Menghua
Dai, Lorena Gonzalez, and Yuman Fong).
31 Signaling Pathways and Rationale for Molecular Therapies in
Hepatocellular Carcinoma (Augusto Villanueva, Clara Alsinet, and
Josep M. Llovet).
32 Novel Therapies Targeted at Signal Transduction in Liver Tumors, (Fidel
D. Huitzil-Melendez, Ghassan K. Abou-Alfa, and Michael A. Morse).
33 Induction of Apoptosis in Liver Tumors (Markus Selzner and
Pierre-Alain Clavien).
34 Antiangiogenic Agents for Liver Tumors (Mathijs Vogten, Emile E.
Voest, and Inne H.M. Borel Rinkes).
35 Integrative Oncology: Alternative and Complementary Treatments (Barrie
R. Cassileth and Jyothirmai Gubili).
Section 7 Special Tumors, Population, and Special Considerations.
Introduction (Stefan Breitenstein and Pierre-Alain Clavien).
36 Liver Metastases from Endocrine Tumors (Clayton D. Knox and C.
Wright Pinson).
37 Uncommon Primary and Metastatic Liver Tumors (Stefan Breitenstein,
Ashraf Mohammad El-Badry, and Pierre-Alain Clavien).
38 Liver Tumors in Special Populations (Tadahiro Uemura, Akhtar Khan,
and Zakiyah Kadry).
39 Malignant Liver Tumors in Children (Xavier Rogiers and Ruth De
Bruyne).
40 Liver Tumors in Asia (Norihiro Kokudo, Sumihito Tamura, and
Masatoshi Makuuchi).
41 Liver Tumors in South America (Lucas McCormack and Eduardo de
Santibañes).
42 Liver Tumors in Africa (Michael C. Kew).
43 Anesthetic Management of Liver Surgery (Marco P. Zalunardo).
44 Qualitative and Economic Aspects of Liver Surgery (René
Vonlanthen, Ksenija Slankamenac, and Christian Ernst).
Index.
